2005학년도 편입학

의학부 수강능력시험 문제지

    A형

2005 학년도 의학부 수강능력 평가 문제지 - 유형 A

(각 문항 0.5 점)

※ For each question, choose the ONE BEST answer.

[1] Which of the following statements is false? 

① Most disease states are multi-factorial.

② Virus nucleic acids act as toxins and poison cells.

③ The vast majority of virus infections do not result in disease.

④ Inflammation, fever, headaches and skin rashes are frequently not caused by virus replication, but the immune response to virus infection.

[2] Transformed cells may not display :

① Loss of anchorage dependence

② Increased expression of p53

③ Decreased requirements for growth factors

④ Colony formation in semi-solid media

[3] Which of the following mechanisms is NOT involved in the pathogenesis of AIDS?   

① New antigenic variants of HIV constantly arise during the course of infection.

② Apoptosis 

③ Insertional activation of oncogenes

④ Superantigens

[4] It is more advantageous for the human body to store fuel as triacylglycerol in adipose tissue than as protein in muscle because adipose triacylglycerol stores contain 

① more calories and more water

② less calories and less water

③ less calories and more water

④ more calories and less water

[5] The oxidation of acetyl CoA by the citric acid cycle plays a major role in providing energy in each of the following tissues EXCEPT

① muscle

② brain

③ liver

④ red blood cells  

[6] Which of the following enzymes is NOT involved in DNA repair?

① ligase

② reverse transcriptase

③ an endonuclease

④ a glycosylase

Questions [7-9]

In the diagram shown below, the letters indicate the phases of the cell cycle. For each statement, select the letter corresponding to the most appropriate phase.

[7] Anticancer drugs inhibit replication.

① A

② B

③ C

④ D

[8] Screening tests for chromosomal abnormalities can be performed.

① A

② B

③ C

④ D

[9] Liver cells enter this phase when they have been stimulated to divide.

① A

② B

③ C

④ D

[10] A 20-year-old woman with diabetes mellitus was admitted to the hospital in a semiconscious state with fever, nausea, and vomiting. Her breath smelled of acetone. A urine sample was strongly positive for ketone bodies. Which of the following statements about this woman is TRUE?

① Glucagon should be administered to stimulate glycogenolysis and gluconeogenesis in the liver.

② An insulin injection would decrease her ketone body production.

③ A blood glucose test would probably show that her blood glucose level was below 80 mg/dl.

④ She should be given a glucose infusion to regain consciousness.

[11] A cDNA clone library is a collection of clones representing

① the entire genome of the sample tissue

② all protein-coding gene sequences in the genome of the sample tissue

③ all intronic sequences of genes expressed in the sample tissue

④ the mRNAs expressed in the sample tissue

[12] Each cycle in the polymerase chain reaction involves the following steps:

① Polymerization then annealing then denaturation

② Denaturation then polymerization then annealing

③ Denaturation then annealing then polymerization

④ Denaturation then polymerization then sequencing

[13] The side chains of the amino acids serine, asparagine, and glutamine are all

① normally negatively charged at pH 7

② normally positively changed at pH 7

③ able to interact with water

④ hydrophobic     

[14] Proteins cannot usually be denatured by

① oxygen

② concentrated urea solution

③ strong acid

④ concentrated ethanol solutions

[15] Cdk1 can be only fully active when

① It is phosphorylated on threonine 14.

② It is phosphorylated on tyrosine 15.

③ It is bound to cyclin A.

④ It is dephosphorylated by Cdc25.

[16] Which of the following statements about eicosanoid hormones is NOT correct?

① The three major classes of eicosanoid hormones are the prostaglandins, the leukotrienes, and the thromboxanes.

② The eicosanoid hormones are derived from arachidonic acid.

③ The eicosanoid hormones are very potent and exert global effects because they are widely distributed by the circulatory system.

④ Prostaglandin precursor is derived from phospholipids.

[17] The 20 amino acids found in proteins are coded by

① 59 codons

② 60 codons

③ 61 codons

④ 63 codons

[18] The lysosomal sorting signal is

① N-acetyl-glucosamine

② mannose-6-phosphate

③ ribose-6-phosphate

④ asparagine

[19] Which of the following substances is an endogenous pyrogen?

① Interleukin (IL)-1

② IL-2

③ IL-3

④ IL-4

[20] Which of the following is a factor made by T cells that is cytotoxic to certain tumor cells?

① IL-4

② IL-6

③ IFN-g

④ TNF-b

[21] Which statement regarding T cells is true?

① They mature in the bursa of Fabricius or bursal equivalent.

② They are involved in humoral and cell-mediated immunity.

③ They are found in the germinal centers of lymph nodes and the spleen.

④ They are progenitors of plasma cells.

[22] The role of macrophages in the immune response includes all of the following functions EXCEPT

① antigen engulfment

② production of IL-2

③ production of endogenous pyrogen

④ production of IL-1

[23] Unlike facilitated diffusion, active transport is 

① sensitive to the concentration of the component only one side of the membrane (the loading side)

② insensitive to the concentration of the component on the other side of the membrane

③ known to saturate at relatively low component concentrations

④ all of the above

[24] The most numerous leukocytes are the    

① lymphocytes

② monocytes

③ eosinophils

④ neutrophils

[25] Blood in the pulmonary vein is rich in       

① oxyhemoglobin

② carbaminoglobulin

③ hemoglobin

④ carbon dioxide

[26] Seed from a self-pollinated gold flowering plant produce 56 charcoal, 130 gold, and 61 beige flowering plants. The plant is    

① heterozygous recessive

② heterozygous with incomplete dominance

③ heterozygous with complete dominance

④ homozygous with incomplete dominance

[27] Natural selection may cause  

① evolution of a population

② a change in gene frequency in a population

③ adaptation of the population to the prevailing conditions

④ All of the above are correct.

[28] Which of the following characteristics of components is shared by skeletal and smooth muscle?